An unusual case of intrathoracic Castleman‘s Disease

Authors

  • Rachel Schoon Class of 2016, Faculty of Medicine, Dalhousie University
  • Liam Mulroy Department of Radiation Oncology, Faculty of Medicine, Dalhousie University
  • Zhaolin Xu Department of Pathology and Laboratory Medicine, Faculty of Medicine, Dalhousie University
  • Drew Bethune Division of Thoracic Surgery, Faculty of Medicine, Dalhousie University

DOI:

https://doi.org/10.15273/dmj.Vol42No1.6437

Abstract

Castleman's disease (CD) is a rare, non-clonal disease of the lymph nodes that may develop at a single site (unicentric form) or multiple sites (multicentric form) throughout the body. Histopathologically, CD is differentiated into a hyaline vascular variant, a plasma cell variant and a mixed cell type. Classically, unicentric CD is of the hyaline vascular variety while multicentric disease is of the plasma cell or mixed cellularity forms. We report an asymptomatic patient whose imaging revealed isolated left hilar lymphadenopathy. After thoracotomy, lymph node excision biopsy was performed, and histopathological examination revealed plasma cell histology. Unicentric plasma cell presentation is a rarely seen variant of CD. 

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Published

2015-11-12

How to Cite

Schoon, R., Mulroy, L., Xu, Z., & Bethune, D. (2015). An unusual case of intrathoracic Castleman‘s Disease. DALHOUSIE MEDICAL JOURNAL, 42(1). https://doi.org/10.15273/dmj.Vol42No1.6437

Issue

Vol. 42 No. 1 (2015)

Section

Case Report

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